The mutational landscape of Staphylococcus aureus during colonisation
Published in bioRxiv, 2023
Recommended citation: Coll F, Blane B, Bellis K, et al. The mutational landscape of Staphylococcus aureus during colonisation. bioRxiv. 2023 https://www.biorxiv.org/content/10.1101/2023.12.08.570284v1
This study provides the most comprehensive picture to date on the heterogeneity of adaptive genetic changes that occur in S. aureus during colonisation, revealing the importance of specific nitrogen metabolic adaption, loss of quorum sensing and antibiotic resistance for successful human colonisation. Here I analysed a dataset of 7,150 S. aureus colonisation isolates from 1,593 subjects and identified novel adaptive variation that warrant further characterisation.
Recommended citation: Coll F, Blane B, Bellis K, et al. The mutational landscape of Staphylococcus aureus during colonisation. bioRxiv. 2023