Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis
Published in Nature Genetics, 2018
Recommended citation: Coll F, Phelan J, Hill-Cawthorne GA, et al. Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis. Nature Genetics. 2018;50(2):307-316. doi:10.1038/s41588-017-0029-0 https://www.nature.com/articles/s41588-017-0029-0
This was one of the largest bacterial GWAS published at the time, where a GWAS approach was applied to a diverse collection of 6,450 M. tuberculosis clinical isolates, from 30 different countries and varying degrees of drug resistances, to uncover novel mutations and epistatic interactions associated with drug resistance
Recommended citation: Coll F, Phelan J, Hill-Cawthorne GA, et al. Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis. Nature Genetics. 2018;50(2):307-316. doi:10.1038/s41588-017-0029-0